Gulf Coast Pain Management
January 2012

Greetings!

We recently received this very important letter from Endo Pharmaceuticals regarding medications that you may have had prescribed to you for your pain management.

IMPORTANT NEWS REGARDING YOUR MEDICATIONS
January 2012

Dear Patient,

If you are currently taking any of the following medicines, please read this important information:

• OPANA® ER (oxymorphone hydrochloride) Extended-Release Tablets CII
• OPANA® (oxymorphone hydrochloride) Tablets CII
• Oxymorphone Hydrochloride Tablets CII
• PERCOCET® (oxycodone hydrochloride and acetaminophen, USP) Tablets CII
• PERCODAN® (oxycodone hydrochloride and aspirin, USP) Tablets CII
• ENDOCET® (oxycodone hydrochloride and acetaminophen, USP) Tablets CII
• ENDODAN® (oxycodone hydrochloride and aspirin, USP) Tablets CII
• Morphine Sulfate Extended-Release Tablets CII
• ZYDONE® (hydrocodone bitartrate/acetaminophen tablets, USP) CIII

Because of potential packaging issues at the manufacturing facility, there is a rare possibility that a wrong tablet may be in your bottle.

Endo is aware of only three product mix-ups with respect to these products since 2009, of which all three were detected by pharmacists. We are not aware of any patient having experienced a confirmed product mix-up and there have been no adverse events attributable to a product mix-up. We believe the likelihood of product mix-up reaching a patient is remote.

As a precautionary measure, we recommend that you:

Look at Your Medicine: We are asking you to look carefully at the tablets in your medicine bottle to make sure they all look the same.

Check Your Tablets: If you are not sure how the tablets should look, please refer to the visual guide attached to this letter or visit www.endo.com and check your tablets against the pictures provided. If all the tablets in your bottle look exactly the same, you should continue to take your medication as directed by your health care professional.

Talk to Your Pharmacist: If you discover that any of the tablets in your bottle are a different color or shape from the others, you should promptly take the medicine back to your pharmacy so the pharmacist can review the contents. Your pharmacist will be able to assist you.

Please contact Endo Customer Service at 1-800-462-3636 if you have any additional questions or concerns.

Sincerely,

Diane K. Jorkasky, M.D., FACP
Senior Vice President Clinical Development and Chief Medical Officer

Most of the patients with potential involvement should have received some sort of notification through their pharmacist. We value as a patient. It is our top priority to deliver safe, effective pain management for you, your family, and friends and notify you of any important issues regarding your care.

Should you have any questions or concerns regarding this issue, please do not hesitate to contact the office, (727)789-0891.

Or email us through our HIPAA compliant online services at www.gulfcoastpain.yourmd.com.

Sincerely,

Lynne Carr Columbus, D.O.
President, Gulf Coast Pain Management